The Brain’s Predictive Power: A Conversation with Georg Keller

In this episode of Neurovoyagers, we take an exciting journey into the world of cortical processing and predictive models with Georg Keller, a senior group leader at the Friedrich Miescher Institute for Biomedical Research in Basel, Switzerland. Georg shares his unique career path, from theoretical physics to cutting-edge neuroscience, offering insights into how internal models shape our perception of the world.

Georg reveals how his early days as a “cheeky student” helped him challenge existing theories and spark new discoveries, including the famous "error cells" in songbirds. We also delve into his current research on cortical circuits, predictive processing, and antipsychotic drugs—topics that could shape the future of neuroscience and treatment for conditions like psychosis.

As a passionate adventurer, Georg also shares his need for adrenaline-filled activities like paragliding and motocross to balance the intellectual demands of science. It’s a fascinating discussion about pushing boundaries, both in the lab and in life.

Listen now to hear how Georg Keller is navigating the complex world of the brain—both inside and outside the lab!

Links and Resources:

• Learn more about Georg Keller’s research at Friedrich Miescher Institute
• Connect with Georg Keller on X or LinkedIn.
• The Book by Lisa Feldman Barrett that Georg recommends